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Milk Thistle Medication Huntington WV

Milk thistle extract, the first substance extracted from the crushed seeds, contains up to 80 percent silymarin, the main active constituent. In contrast, the silymarin content of unprocessed seeds may fall as low as 4 percent silymarin.

Tri-State Veterinary Hospital
(304) 525-8387
6474 Merritts Crk Rd
Huntington, WV
 
Proctorville Animal Clinic
(740) 886-9424
6129 County Road 107
Proctorville, OH

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Help For Animals Inc
(304) 736-8555
1 Humane Way
Barboursville, WV

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Tambling, Fred R, Dvm - Barboursville Veterinary
(304) 736-8939
6310 Farmdale Rd
Barboursville, WV

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Martin Veterinary Clinic
(606) 324-8036
1426 Grandview Dr
Ashland, KY

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Equine Medical Ctr
(740) 867-0066
764 County Road 31
Chesapeake, OH

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Ayers Animal Hospital
(304) 529-6049
1514 Norway Ave
Huntington, WV

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Barboursville Veterinary
(304) 736-8939
6310 Farmdale Rd
Barboursville, WV

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Olson Animal Hospital
(304) 736-1677
5980 Us Route 60 E
Barboursville, WV

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Dyer, Mike, Dvm - Ashland Animal Clinic
(606) 324-2984
3101 13th St
Ashland, KY

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Milk Thistle Shows Promising Applications in Treating Liver Disease, Cancer

When Pliny the Elder prescribed milk thistle 2,000 years ago, he did so for a variety of health concerns, including serpent bites, melancholy, plague and milk production, in addition to “carrying off bile.” 1 , 2 Now, the popularity of milk thistle is soaring, not only for treating chronic liver problems for which it is best known, but also for its ability to protect other organs from the damaging effects of radiation, chemotherapy, other xenobiotics and chronic disease. 3 For example, its antioxidant actions decrease gentamicin-induced nephrotoxicity in dogs; 4 milk thistle also promotes kidney function in patients with end-stage diabetic nephropathy. 5

What’s in It
Milk thistle extract, the first substance extracted from the crushed seeds, contains up to 80 percent silymarin, the main active constituent. 6 In contrast, the silymarin content of unprocessed seeds may fall as low as 4 percent silymarin. 7 Some manufacturers standardize the silymarin content to ensure equivalence between batches. Silibinin (or silybin), a semi-purified fraction of silymarin, acts as an important marker for research to track pharmacokinetics and ensure adequate plasma and target tissue concentrations. 8 Monitoring pharmacokinetics becomes especially important when studying phytomedicinals exhibiting poor or erratic bioavailability, as do the flavonolignans comprising silymarin. Complexing silibinin with phophatidylcholine dramatically improves oral availabi...

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