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Milk Thistle Medication Martinsville IN

Milk thistle extract, the first substance extracted from the crushed seeds, contains up to 80 percent silymarin, the main active constituent. In contrast, the silymarin content of unprocessed seeds may fall as low as 4 percent silymarin.

Animal Hospital-Martinsville
(765) 349-7387
392 S Main St
Martinsville, IN

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Neuter Scooter
(812) 332-7525
3789 E Bethel Ln
Bloomington, IN

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Foley, Sarah, Dvm - College Mall Veterinary Hosp
(812) 334-1400
4517 E Morningside Dr
Bloomington, IN

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Cox, Mary Alice, Dvm - Bloomington Veterinary Hosp
(812) 339-6115
115 N Smith Rd
Bloomington, IN

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Good Shepherd Veterinary Services
(317) 422-8448
250 S State Road 135
Bargersville, IN

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Country Critters Veterinary
(317) 996-2727
125 S Chestnut St
Monrovia, IN

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College Mall Veterinary Hosp
(812) 334-1400
4517 E Morningside Dr
Bloomington, IN

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College Mall Veterinary Hospital
(812) 334-1400
4517 E Morningside Dr
Bloomington, IN

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Williamson Emily Dvm
(317) 422-5255
751 N Road 700 W
Bargersville, IN

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Towne & Country Vet Clinic
(812) 332-1429
3140 N Smith Pike
Bloomington, IN

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Milk Thistle Shows Promising Applications in Treating Liver Disease, Cancer

When Pliny the Elder prescribed milk thistle 2,000 years ago, he did so for a variety of health concerns, including serpent bites, melancholy, plague and milk production, in addition to “carrying off bile.” 1 , 2 Now, the popularity of milk thistle is soaring, not only for treating chronic liver problems for which it is best known, but also for its ability to protect other organs from the damaging effects of radiation, chemotherapy, other xenobiotics and chronic disease. 3 For example, its antioxidant actions decrease gentamicin-induced nephrotoxicity in dogs; 4 milk thistle also promotes kidney function in patients with end-stage diabetic nephropathy. 5

What’s in It
Milk thistle extract, the first substance extracted from the crushed seeds, contains up to 80 percent silymarin, the main active constituent. 6 In contrast, the silymarin content of unprocessed seeds may fall as low as 4 percent silymarin. 7 Some manufacturers standardize the silymarin content to ensure equivalence between batches. Silibinin (or silybin), a semi-purified fraction of silymarin, acts as an important marker for research to track pharmacokinetics and ensure adequate plasma and target tissue concentrations. 8 Monitoring pharmacokinetics becomes especially important when studying phytomedicinals exhibiting poor or erratic bioavailability, as do the flavonolignans comprising silymarin. Complexing silibinin with phophatidylcholine dramatically improves oral availabi...

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